Research Abstracts
Selected and abstracted by Bette Hartley, M.L.S., and John H. Greist, M.D., Madison Institute of Medicine. The following is a selection of research articles on compulsive hoarding in current scientific journals.
Paroxetine treatment of compulsive hoarding.
Journal of Psychiatric Research 41(6): 481-487, 2007.
Objective: Compulsive hoarding, found in many patients with obsessive-compulsive disorder (OCD), has been associated with poor response to serotonin reuptake inhibitor (SRI) medications in some reports. However, no prior study has quantitatively measured response to standardized pharmacotherapy in compulsive hoarders. We sought to determine whether compulsive hoarders would respond as well as non-hoarding OCD patients to the SRI, paroxetine. Methods: Seventy-nine patients with OCD (32 patients with the compulsive hoarding syndrome and 47 patients without prominent hoarding symptoms) were treated openly with paroxetine (mean dose 41.6 ± 12.8 mg/day; mean duration 80.4 ± 23.5 days) according to a standardized protocol, from 3/1993 to 7/2005. All subjects were free of psychotropic medication for at least four weeks prior to study entry. No psychotherapy or psychotropic medications except paroxetine were allowed during the study period. Subjects were assessed before and after treatment with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Scale (Ham-A), Global Assessment Scale (GAS), and Clinical Global Impression/Improvement (CGI) scale. Results: Both compulsive hoarders and non-hoarding OCD patients improved significantly with treatment (p < 0.001), with nearly identical changes in Y-BOCS, HDRS, Ham-A, and GAS scores. There were no significant differences between groups in the proportions of patients who completed or responded to treatment. Hoarding symptoms improved as much as other OCD symptoms. Conclusions: Compulsive hoarders responded as well to paroxetine treatment as non-hoarding OCD patients, suggesting that SRI medications are effective for compulsive hoarding. Controlled trials of SRI medications for compulsive hoarding are now warranted.
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An open trial of cognitive-behavioral therapy for compulsive hoarding.
Beh. Res. Ther. 45(7): 1461-1470, 2007.
The aim of the present study was to provide preliminary data on the efficacy of a new cognitive-behavioral treatment (CBT) for compulsive hoarding. Fourteen adults with compulsive hoarding (10 treatment completers) were seen in two specialty CBT clinics. Participants were included if they met research criteria for compulsive hoarding according to a semistructured interview, were age 18 or above, considered hoarding their main psychiatric problem, and were not receiving mental health treatment. Patients received 26 individual sessions of CBT, including frequent home visits, over a 7-12 month period between December 2003-February 2005. Primary outcome measures were the Saving Inventory- Revised (SI-R), Clutter Image Rating (CIR), and Clinician's Global Impression (CGI). Significant decreases from pre- to post-treatment were noted on the SI-R and CIR, but not the CGI-severity rating. CGI-Improvement ratings indicated that at mid-treatment, 40% (n = 4) of treatment completers were rated 'much improved' or 'very much improved;' at posttreatment, 50% (n = 5) received this rating. Adherence to homework assignments was strongly related to symptom improvement. CBT with specialized components to address problems with motivation, organizing, acquiring and removing clutter appears to be a promising intervention for compulsive hoarding, a condition traditionally thought to be resistant to treatment.
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Clinical features of children and adolescents with obsessive-compulsive disorder and hoarding symptoms.
Comprehensive Psychiatry 48(4): 313-318, 2007;
Objective: This study was conducted to examine whether pediatric patients with obsessive-compulsive disorder (OCD) and hoarding symptoms differed in terms of clinical characteristics from pediatric OCD patients without hoarding symptoms. Method: Eighty children and adolescents with OCD (range, 7-17 years) completed clinician-administered and parent- and child-report measures of OCD symptom severity, impairment, and emotional and behavioral symptoms. Results: Twenty-one youth endorsed significant hoarding symptoms. Relative to nonhoarders, youth with hoarding symptoms had worse insight, more magical thinking obsessions, and ordering/arranging compulsions than nonhoarders, higher levels of anxiety, aggression, somatic complaints, and overall externalizing and internalizing symptoms. Higher rates of panic disorder were found in youth with hoarding symptoms although other comorbidity rates did not differ. Conclusions: These findings in children are partially consistent with studies in adults, and suggest that pediatric patients with hoarding symptoms may exhibit a unique clinical presentation.
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Neuropsychological impairment associated with compulsive hoarding.
Beh. Res. Ther. 45(7): 1471-1483, 2007.
A group of patients with compulsive hoarding (n = 30) was compared to a mixed clinical group (n = 30) and a nonclinical community group (n = 30) on laboratory tests of information-processing features hypothesized to be central to hoarding (memory, attention, and decision-making). Hoarding patients demonstrated slower and more variable reaction time, increased impulsivity, greater difficulty distinguishing targets and nontargets, and worse spatial attention relative to comparison groups. Multiple regression analyses demonstrated that slower reaction time and increased impulsivity were significantly related to hoarding symptoms over and above the effect of depression, schizotypy, and other obsessive-compulsive disorder (OCD) symptoms. There were no group differences on a test of emotion-based decision-making. Results are discussed in terms of previous findings and theoretical models of compulsive hoarding.
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Hoarding in obsessive-compulsive disorder: Results from the OCD Collaborative Genetics Study.
Beh. Res. Ther. 45(4): 673-686, 2007.
Hoarding behavior occurs frequently in obsessive-compulsive disorder (OCD). Results from previous studies suggest that individuals with OCD who have hoarding symptoms are clinically different than non-hoarders and may represent a distinct clinical group. In the present study, we compared 235 hoarding to 389 non-hoarding participants, all of whom had OCD, collected in the course of the OCD Collaborative Genetics Study. We found that, compared to non-hoarding individuals, hoarders were more likely to have symmetry obsessions and repeating, counting, and ordering compulsions; poorer insight; more severe illness; difficulty initiating or completing tasks; and indecision. Hoarders had a greater prevalence of social phobia and generalized anxiety disorder. Hoarders also had a greater prevalence of obsessive-compulsive and dependent personality disorders. Five personality traits were independently associated with hoarding: miserliness, preoccupation with details, difficulty making decisions, odd behavior or appearance, and magical thinking. Hoarding and indecision were more prevalent in the relatives of hoarding than of non-hoarding probands. Hoarding in relatives was associated with indecision in probands, independently of proband hoarding status. The findings suggest that hoarding behavior may help differentiate a distinct clinical subgroup of people with OCD and may aggregate in some OCD families. Indecision may be a risk factor for hoarding in these families.
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Categorization in compulsive hoarding.
Beh. Res. Ther. 45(1): 63-72, 2007.
Based on hypothesizing about the role of information processing, and in particular, underinclusive categorization in compulsive hoarding, this study examined categorization processes in people with clinically significant compulsive hoarding problems. Twenty-one participants with primary compulsive hoarding, 21 with OCD without hoarding, and 21 non-psychiatric controls completed three categorization tasks. Hoarding and OCD participants reported significantly more distress prior to each of the three tasks than did controls. On tasks sorting common household items, the groups did not differ on the number of piles created nor on the amount of time taken to sort. However, on a task sorting personally relevant items, hoarding participants took more time, created more piles, and reported more anxiety than non-psychiatric controls. Hoarders also took more time than the OCD group, and tended to create more piles. Hoarding severity was correlated with the number of piles created, but only when the objects were personally relevant. Results support under-inclusive categorizing for people with compulsive hoarding, but the effect was largely confined to objects of personal relevance.
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Order Code: OC #18731
Hoarding behaviors in a large college sample
Behav. Res. Ther. 41(2): 179-194, 2003;
Hoarding behaviors occur in many clinical syndromes but are most commonly linked to obsessive-compulsive disorder. Surprisingly little empirical work has examined the nature of hoarding behaviors despite their association with significant distress and impairment. The current study examined hoarding in 563 unselected college students. Using principal components analysis, we identified four domains of hoarding behaviors as measured by the 26-item Saving Inventory-Revised: Difficulty Discarding, Acquisition Problems, Clutter, and Interference/Distress. All four domains and total hoarding behaviors were strongly related to hoarding beliefs and to obsessive-compulsive (OC) symptoms. Hoarding behaviors were most strongly correlated with subscales of an OC disorder (OCD) measure assessing hoarding and obsessions and least strongly correlated with the washing subscale. Hoarding behaviors also showed significant, but more modest, correlations with social anxiety, depressive symptoms, and worry. However, worry was not found to contribute unique variance to the prediction of hoarding behaviors. Of greatest note, hoarding behaviors showed a surprisingly strong relationship with anxiety sensitivity. This was similar in magnitude to the relationship between hoarding and OCD symptoms. Results are interpreted and lines of future research are proposed, with particular emphasis on further elucidating the relationship between hoarding behaviors and anxiety sensitivity.
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Order Code: OC #19777
Cognitive and behavioral treatment of compulsive hoarding
Brief Treatment And Crisis Intervention 3(3): 323-337, 2003;
Compulsive hoarding appears to be a common variation of obsessive-compulsive disorder that is associated with elevated anxiety, depression, and disability. It is commonly accompanied by a variety of comorbid conditions. In this article, the authors present a model for understanding this multifaceted problem, from which they derive specific treatment interventions. These treatements pertain to problems with information processing; excessive attachment with strong beliefs pertinent to saving possessions; avoidance of distress associated with discarding or making decisions about possessions; and excessive acquisition and difficulty discarding possessions. A case example illustrates these problems and the methods of assessment, and interventions that proved successful during cognitive and behavioral treatment.
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Order Code: OC #19812
Cognitive aspects of compulsive hoarding
Cognitive Therapy And Research 27(4): 463-479, 2003;
Hoarding of possessions is thought to be influenced by deficits in information processing, emotional attachments, and erroneous beliefs about possessions. This study examines hypothesized beliefs about possessions using an instrument developed for this purpose, the Saving Cognitions Inventory (SCI). Participants were individuals with compulsive hoarding (n = 95), obsessive-compulsive disorder without hoarding (n = 21), and community controls (n = 40). An exploratory factor analysis yielded four factors similar to those hypothesized, representing emotional attachment, concerns about memory, control over possessions, and responsibility toward possessions. Subscales created based on these factors were internally consistent, and showed known groups, convergent and discriminant validity. Regression analyses indicated that three of the four subscales (memory, control, and responsibility) significantly predicted hoarding severity after age, mood state, OCD symptoms and other OCD-related cognitive variables were entered. Interestingly, difficulty with decision making also proved to be an important predictor of hoarding behavior. Implications for understanding and treating hoarding are discussed and study limitations are noted.
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Order Code: OC #20034
Compulsive hoarding: Current status of the research
Clin. Psychol. Rev. 23(7): 905-927, 2003;
This article reviews the literature on compulsive hoarding. This includes the definition and manifestations of the problem and a conceptual model for understanding hoarding behavior. This model addresses information-processing deficits (e.g., attention, organization, memory, decision making), beliefs about emotional attachments to possessions, and distress and avoidance. Research regarding the diagnostic categorization of hoarding, its course and phenomenology, and evidence to support the model are presented. The limited research on treatment provides evidence that current serotonergic medications for OCD are largely ineffective for treating hoarding, but cognitive and behavioral treatments, especially those focused on deficits identified in the model, have some utility. Recommendations for further research on the psychopathology and treatment of hoarding are provided.
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Copies of these articles can be ordered from the Madison Institute of Medicine at (608) 827-2470. Please refer to the particular article by the Order Code shown directly above the title of the article.
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